Problem description-
Server Error in ‘/virtual directory name’ Application.
Error in File UNKNOWN.RPT:
The request could not be submitted for background processing.
Description: An unhandled exception occurred during the execution of the current web request. Please review the stack trace for more information about the error and where it originated in the code.
Exception Details: System.Runtime.InteropServices.COMException: Error in File UNKNOWN.RPT: The request could not be submitted for background processing.
Solution-
This is most likely a permission error in C drive. To fix this please follow these steps-
Open My Computer > Right click ‘C’ drive then properties > Security tab > Click Advanced > in ‘Permissions tab’ click ‘Add’ > Add ‘Network Service’ > in the ‘Apply onto’ drop down list make sure ‘This folder only’ is selected and no other should be selected > Make ‘Read Attributes’ and ‘Read Permissions’ are checked > Click Ok > Also make sure ‘Replace permission entries on all child objects’ is NOT checked.
***Note: If you incorrectly set to anything other than ‘This folder only’ in ‘Apply onto’ dropdown list will result in severe permission issues and all of your sites will prompt for authentication so handle withe extra care.***

HI thanks for your great articel
Thank you much… this was a grand slam home run for me after spending the better part of two days reading through forums and attempting what seems like a 100 different combinations of adjusting security settings / applying hot fixes etc…
Glad this got fixed
Feel free to ping me for any kind of server issues.
Cheers!
Arun